This trade report explores the business environment challenges faced by female-owned businesses in Africa using several data clustering approaches. By analysing World Bank enterprise survey data, we identify six distinct policy clusters among African countries based on priority policy areas. The clusters reveal significant regional patterns and unique country-specific challenges, emphasising issues such as access to finance, electricity supply, political instability, and competition from the informal sector. The findings highlight the need for tailored policy interventions and regional cooperation to address both common and unique challenges.